Ogunlesi is the son of Nigeria's first Professor of Medicine. He attended King's College Lagos and Oxford University, where he got a BA First Class Honours in Philosophy, Politics and Economics. He bagged a Law Degree and MBA at Havard University.
He is also the chairman of Africa Finance Corporation, a Pan-African infrastructure investment firm. He is also a member of the Board of Directors of Goldman Sachs, an American multinational investment banking firm.
He is married to Dr Amelia Quist Ogunlesi, a New York based optometrist.